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Nutritional supplement

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One capsule contains:

  • Luthein esters                                                        6 mg,
  • Standardized Bilberry (Vaccinium myrtillus) extract    200 mg,
  • Standardized Ginkgo (Ginkgo biloba) extract             30 mg,
  • Beta carotene                                                       3 mg,
  • Vitamin B1                                                        8,89 mg,
  • Vitamin B6                                                        8,54 mg,
  • Biotin                                                                0,9 mg,
  • Vitamin B12                                                      0,3 mcg,
  • Vitamin C                                                            75 mg,
  • Vitamin E                                                            10 mg,
  • Selenium                                                           100 mcg.


Recommendations for use:

  • eyesight strengthening,
  • to help maintain healthy eyes and good vision.


Action of active substances

Lutein

Lutein is a lipid soluble bioactive pigment that is synthesized in plants. Green leafy vegetables, especially spinach, contain it most. Lutein is not produced in the organism. It has to be consumed with food. Statistics show that only 23 percent of people consume enough fruits and vegetables and receive enough lutein. It is necessary to supplement nutrition with lutein for everyone who does not like vegetables. Lutein accumulates in macula of the retina and protects it from degradation, improves eye perfusion, protects macula from harmful ultraviolet ray effect and arteries from the development of the atherosclerosis. Lutein is one of the most important pigments in macula that protects from the development of glaucoma and cataract, acts as antioxidant and maintains good eyesight. Macula degeneration risk decreases even 90 percent if the consumed amount of lutein is sufficient. 6 mg of lutein is an optimal and sufficient daily dose.

Vitamin C and E

They have antioxidative properties, protect eyes from harmful ultraviolet ray effect and neutralize free radicals.

Beta carotene

Suppresses the oxidation processes of free radicals that harm our vision, improves eye capillarization and supply of eye and muscle nerves with necessary substances.

Bilberry anthocyanin

It is water soluble pigments that have potent antioxidative properties and slow the development of cataract and degradation of retina.

Ginkgo biloba extract

Ginkgo biloba extract contains substances that improve vision in case of senile retinal degeneration and diabetic retinopathy, improve the circulation in brain, protect nerve cells from harmful effect of various factors, regulate tonicity and elasticity of blood vessels, ensure better central and peripheral circulation.

B group vitamins

Improve brain and peripheral circulation and nervous system activity.

Scientific researches demonstrating the efficiency

* Double blind, placebo controlled, randomized study showed that administration of lutein increases the density of the pigment in retina and improves the visions in case of retinal degeneration. (Koh H-H, Murray IJ, Nolan D, et al. Plasma and macular responses to lutein supplement in subjects with and without age-related maculopathy: a pilot study. Exp Eye Res 2004; 79: 21-27.)
* American scientists data show that 6 mg of lutein is an optimal and sufficient daily dose. It reduces retinal degeneration 57 percent and cataract development – 22 percent for women and 19 percent for men. (Seddon JM, Ajani UA, Sperduto RD, et al. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. JAMA 1994:272:1413-20.
* In 2002 a 6 months study was published that lutein protects photoreceptors in retina from harmful effect of ultraviolet rays. High lutein concentration in macula is very important and should be as high as possible. (November 2002 issue of Experimental Eye Research)
* USA experimental research showed that ginkgo biloba improves the circulation, neutralizes free radicals, may be useful in case of retinal degeneration, diabetic retinopathy and glaucoma. (Doly et al., 1986; DeFeudis, 1991; Baudouin et al., 1999; Chung et al., 1999)

Literature:

1.Beatty S et al. Macular pigment and risk for age-related macular degeneration in subjects from a Northers European population. Invest Ophthalmom Vis Sci 2001 Feb;42(2):439-46.
2.Moeller SM et al. The potential role of dietary xanthophylls in catartact and age-related macular degeneration. J Am Coll Nutr 2000 Oct;19(5Suppl):522d-527S.
3.Berendschot TT et al. Influence of lutein supplementation on macular pigment, assessed with two objective techniques. Invest Ophthalmol Vis Sci 2000 Oct;41(11):3322-6
4.Haase, J., P. Halama and R. Horr (1996). "[Effectiveness of brief infusions with Ginkgo biloba Special Extract EGb 761 in dementia of the vascular and Alzheimer type]." Z Gerontol Geriatr 29(4): 302-9.
5.Hofferberth, B. (1989). "[The effect of Ginkgo biloba extract on neurophysiological and psychometric measurement results in patients with psychotic organic brain syndrome. A double-blind study against placebo]." Arzneimittelforschung 39(8): 918-22.
6.Mares-Perlman JA, Brady WE, Klein BE, et al. Diet and nuclear lens opacities. Am J Epidemiol. 1995;141:322–334.
7. Hankinson SE, Stampfer MJ, Seddon JM, et al. Nutrient intake and cataract extraction in women: a prospective study. BMJ. 1992;305:335–339.
8. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr. 1999;70:517–521.
9. Chasan-Taber L, Willett WC, Weddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr. 1999;70:509–516.
10. Landrum JT, Bone RA, Kilburn MD. The macular pigment: a possible role in protection from age-related macular degeneration. Adv Pharmacol. 1997;38:537–556.
11.Landrum JT, Bone RA, Kilburn MD. The macular pigment: a possible role in protection from age-related macular degeneration. Adv Pharmacol. 1997;38:537–556.
12. Hammond BR Jr, Wooten BR, Snodderly DM. Density of the human crystalline lens is related to the macular pigment carotenoids, lutein and zeaxanthin. Optom Vis Sci. 1997;74:499–504.
13. Mares-Perlman JA, Fisher AI, Klein R, et al. Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey. Am J Epidemiol. 2001;153:424–432.
14. Hassan K, Hough G, Wang X, et al. Dietary lutein markedly reduces atherosclerotic lesion formation in apolipoprotein null mouse [abstract]. FASEB J. 1999;13:A176.
15.Olmedilla B, Granado F, Blanco I, et al. Lutein, but not alpha-tocopherol, supplementation improves visual function in patients with age-related cataracts: a 2-y double-blind, placebo-controlled pilot study. Nutrition. 2003;19:21–24.
 
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