|
Nutritional supplement 
Composition One capsule contains: Recommendations for use: - for strong immunity,
- to reduce cholesterol and sugar blood levels,
- for strong immunity and healthy skin,
- to improve wound healing.
Action of active substances
Beta glucans Beta glucan, as a natural polysaccharide, is mostly found in medicinal Japanese mushrooms Shiitake, Maitake,
Reishi, yeast, algae and barley. Beta glucan has a versatile action including its ability to effectively and safely
reduce cholesterol and LDL (low density lipoproteins) levels in blood and combat progress of atherosclerosis.
There are clinical researches indicating that intake of Beta glucans reduces total cholesterol levels in blood by
8-10 percent. Beta glucan has also ability to reduce assimilation of carbohydrates, improve sensitivity of tissues
to insulin, improve metabolic processes, and reduce glucose concentration in blood. Beta glucans enhance immunity,
have strong anti-tumor action, stimulate post-surgery and post-injury wound and bedsore healing, and
induce skin renewal. In combination with cytostatics, Beta glucans reinforce the effect of cytostatics and reduce
their negative action on immune system. In addition to the above, Beta glucans have a radioprotective effect and
therefore intake of Beta glucans is strongly recommended for radiotherapy or post-radiotherapy patients. Scientific researches evidencing effect of Beta glucans * In 1991, Kochi (Japan) Medical School carried out double blind placebo controlled research involving 120
throat carcinoma patients. The influence of Beta glucans on growth of the number of killers and immune system
was observed. The number of killers within one and three weeks increased by 34% and 46% respectively.
Moreover, the group treated by Beta glucans showed increased activity of killers (p<0.05). Intake of Beta glucans
increases the number of killers and enhances their activity in addition to its action as immunity booster.
(Clin.Exp.Immunolog.1991;86(2): 229 – 35 Yoneda K., Osaki T., Departament of Oral Surgery, Kochi Medical
Shool,Japan)
* In order to determine the effect of Beta glucans on skin damages resulting from radiotherapy treatment, the US
Cancer Research Institute performed double blind placebo controlled research involving 180 breast cancer female
patients in 1996. One group of patients was treated by radiotherapy and another-by radiotherapy in combination
with Beta glucans. Within 6 months, the combined treatment group showed 30% less skin damages than
the radiotherapy group. Within 11 months, the combined treatment group showed 45% less skin damages than
the radiotherapy group. It became evident that intake of Beta glucans reduces side effects of radiotherapy.
* In 2003, Helwan University (Cairo) carried out double blind randomized placebo controlled research involving
514 stomach cancer patients. One group of patients was treated by cytostatics in combination with Beta glucans
and the other- by cytostatics only. Combination of cytostatics and Beta glucans proved to stop reduction of the
number of lymphocytes and enhance immunity within 4 months. While patients undergoing treatment by cytostatics
showed constantly decreasing number of lymphocytes and failing immune system ( Mutat Res.2003 Nov
10 ;541(1 – 2): 45 – 53. Helwan University, Cairo, Egypt). Dosage
1 capsule 2 to 3 times per day with meals.Literature:
1. Wasser SP, Weis AL, “Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective,” Crit Rev Immunol. 1999; 19(1): 65-96.
2. Bousquet M, Escoula L, Peuriere S, et al., “Immunopharmacologic study in mice of 2 beta-1, 3, beta-1, 6 polysaccharides (scleroglucan and PSAT) on the activation of macrophages and T lymphocytes,” Ann Rech Vet. 1989; 20(2): 165-73.
3. Soltys J, Quinn MT, “Modulation of endotoxin- and enterotoxin-induced cytokine release by in vivo treatment with beta- (1,6)-branched beta- (1,3)-glucan,” Infect Immun. 1999 Jan; 67(1): 244-52.
4. Williams DL, Ha T, Li C, et al., “Inhibiting early activation of tissue nuclear factor-kappa B and nuclear factor interleukin 6 with (1-->3)-beta-D-glucan increases long-term survival in polymicrobial sepsis,” Surgery. 1999 Jul; 126(1): 54-65.
5. Miura NN, Ohno N, Aketagawa J, et al., “Blood clearance of (1-->3)-beta-D-glucan in MRL lpr/lpr mice,” FEMS Immunol Med Microbiol. 1996 Jan; 13(1): 51-57.
|
