Read the whole leaflet carefully before you start taking this medicine.
-    Keep the leaflet for later reference, when necessary.
-    If you have more questions about the product, consult your doctor or pharmacist.  
-    This medicine was prescribed for you personally, so other persons should not use it. The medicine may have adverse effect for their health (even to persons, who suffer from similar symptoms as you).
-    If you experienced a severe side effect or had a side effect that is not specified in this leaflet, inform your doctor or pharmacist about it.
    
In this leaflet:
1.    What is VINPOCETINE-aconitum and when it is used
2.    What you should know before starting to use VINPOCETINE-aconitum
3.    How to use VINPOCETINE-aconitum
4.    Possible side effects
5.    Storage of VINPOCETINE-aconitum
6.    Other information
    
    
1.    WHAT VINPOCETINE-ACONITUM IS IS AND WHAT IT IS USED FOR

VINPOCETINE-aconitum belongs to the group of so-called nootropic medicines.  

Active ingredient: vinpocetine.

    VINPOCETINE-aconitum hard capsules are used to reduce the symptoms of mental conditions or nervous system disorders caused by insufficient blood flow to the brain that appears with aging.  
    
    
2.    WHAT YOU SHOULD KNOW BEFORE TAKING VINPOCETINE-ACONITUM

Do not take VINPOCETINE-aconitum in the following cases:
-    if you are alergic (have increased sensitivity) to vinpocetine or any other ingredient of VINPOCETINE-aconitum.
-    if you had brain haemorrhage lately, or if you suffer from increased blood pressure in the brain.
-    do not give VINPOCETINE-aconitum to children and adolescents.
-    VINPOCETINE-aconitum should not be taken by patients suffering from rare inherited disorder – Lapp lactase defficiency or malabsorption of glucose and galactose.

If you notice symptoms of skin rash, itching, short breath, swollen face, seek for medical advice immediately, as you may be sensitive to the medicine.  

Take special care with VINPOCETINE-aconitum:

Inform your doctor about all your health conditions and illnesses (especially if you have heart disorders, or if your doctor has told you about the changes in your electrocardiography (ECG)). Patients suffering from any of the disorders hereinabove should consult their physician before starting to use VINPOCETINE-aconitum, as they need regular medical monitoring of the treatment.  
Patients with prolonged QT syndrome, as well as those taking medicines to prolong this interval, and using VINPOCETINE-aconitum, need to have regular electrocardiography.
Insufficient information is available on use of this medicine for the treatment of children.

Taking other medicines
Tell your physician or pharmacist, if you are taking or have been taking other medicines lately, including the ones purchased over-the-counter.

Vinpocetine may react with medicines reducing the blood pressure, preparations for heart rhythm disorders (antiarythmics), reducing blood coagulation (anticoagulants) and medicines affecting central nervous system.

This medicine may enhance the effect of Metildopa, so your physician should control your blood pressure regularly during the entire period of treatment with VINPOCETINE-aconitum.
    
Taking VINPOCETINE-aconitum with food and drinks  
VINPOCETINE-aconitum can be taken during meals.
    
Pregnancy and breast-feeding
Do not use VINPOCETINE-aconitum, if you are pregnant or breast-feeding.

Driving and using machines
It is possible that VINPOCETINE-aconitum may interfere with your alertness and ability to drive. Persons using this medicine are advised not to drive and not to operate equipment until the moment their physician determines them to be able to do it safely.
    
Important information about additives used inVINPOCETINE-aconitum
VINPOCETINE-aconitum contains lactose. If your physician has told you of your intolerances of carbohydrates, consult him before starting to use this medicine.
    
    
3.    HOW TO USE VINPOCETINE-ACONITUM

Take VINPOCETINE-aconitum exactly as instructed by your physician. In case of doubt, please consult your doctor or pharmacist.

Adult
It is recommended to take 1–2 capsules (5–10 mg) three times a day for the first 30 days. The dose may be reduced to 1 capsule (5 mg) three times a day later on. Do not take more than 30 mg of vinpocetine a day.

Food may have an impact on the use of the medicine, thus it is recommended to take VINPOCETINE-aconitum during or immediately after the meals.  

The effect of this medicine is felt in about a week, and the strongest effect is felt in approximately three months.

This medicament is most usually well-tolerated, so it can be taken for a long period of time. There is no reaction to immediate stoppage of treatment with vinpocetine.

Elderly patients
Usually there is no need to change the dosage specified hereinabove for elderly patients.

Patients suffering from liver and kidney disorders
There is no need to change the dosage specified hereinabove for patients suffering from liver and kidney disorders.

Children and adolescents
The efficiency of VINPOCETINE-aconitum among children and adolescents has not been tested. Persons under 18 do not recommend to take  this medicine.  

If overdosed, the medicine may cause side effects. Those side effects are usually not dangerous for human health; however, seek medical advice, if side effects occur.

If you took more VINPOCETINE-aconitum than you should
If you overdosed vinpocetine accidentally, seek medical advice or go to the nearest hospital.

If you forgot to take VINPOCETINE-aconitum   
Do not take double dose of medicine in attempt to compensate the missed one.
    
If you stop taking VINPOCETINE-aconitum
    
If you start feeling better do not stop taking the medicine until your doctor tells you to do so.
    
If you have any questions about the use of this medicine consult your physician or pharmacist.
    
    
4.    POSSIBLE SIDE EFFECTS

VINPOCETINE-aconitum, as any other medicine, may cause side effects, although not in all patients.

The most frequent side effects of VINPOCETINE-aconitum solid capsules are headaches, dizziness, reduced blood pressure, dry mouth, nausea, dyspepsia, diabetes and increased amount of cholesterol in the blood.

Some persons seldom may have reduced amount of leucocytes and thrombocytes in the blood, sleep disorders, expressed excitement, anxiety, sleepiness, dizziness, change in perception of smell and taste, laziness, memory disorders, changes in optic nerve disc, hearing disorders, ringing in the ears, heart attack, angina pectoris, slower or quicker heartbeat, cardiac conductive system disorders, palpable heartbeat,  increased blood pressure, redness in the face and neck, inflammation of leg veins, stomach ache, constipation, diarrhoea, vomiting, redness of skin, increased perspiration, itching of skin, hives, skin rash, overall fatigue and sudden waves of heat. Although seldom, some laboratory test results may alter: the test results may show increased concentration of triglicerides, depression of ST segment in electrocardiogram, increased or decreased amount of eosinophils in the blood and altered activity of liver enzymes.

Some patients in very rare cases may experience the following side effects: anaemia, allergic reactions, overly high moods, depression, tremor of limbs, convulsions, redness of conjunctiva, disturbed rhythm of the heart, atrial fibrillation, inconsistent blood pressure, inflammation of dental gums, swallowing disorder, skin inflammation, unpleasant sensations in the chest and decreased body temperature. Some results of laboratory tests may alter very seldom: test results may show increased or decreased amount of leucocytes in the blood, decreased amount of granulocytes, amount of erythrocytes in the blood, shorter period of thrombin and increased body weight.
If you have any of the above mentioned side effects or any side effect that was not specified in this leaflet, inform your physician or pharmacist about it.
    
5.    HOW TO STORE  VINPOCETINE-ACONITUM
    
Keep out of reach of children.
    
Store at temperatures under 25 oC.
Blister packages should be stored in the carton boxes, so that the medicine would be protected from direct sun light.

Do not use VINPOCETINE-aconitum after the term of validity specified on the blister package or the carton box expires. The medicine is suitable for use only by the last day of the specified month.

Do not throw the medicine to the sewerage or together with household waste. Ask you pharmacist about the disposal of unnecessary medicines. Such measures will help to protect nature.
    
    
 6.        FURTHER INFORMATION

What VINPOCETINE-aconitum contains

-    The active ingredient is vinpocetine. Each hard capsule contains 5 mg of vinpocetine.
-    Excipients: microcrystalline cellulose, lactose monohydrate, starch, magnesium stearate, colloidal anhydrous silica dioxide, in the body of the capsule – gelatine, titanium dioxide E 171.

What VINPOCETINE-aconitum looks like and contents of the pack

VINPOCETINE-aconitum hard capsules are white cylindrical capsules filled with white powder.

VINPOCETINE-aconitum is packed in blister packages of 20 capsules. Blister packages are packed in cartons containing 40 or 60 capsules.
Not all the sizes of cartons may be available for supply.


Marketing authorization holder and manufacturer
UAB “Aconitum”
Taikos ave.102,
LT-51195 Kaunas,
Lithuania
Tel. +370 37 328008
Fax: +370 37 338487
E-mail: This e-mail address is being protected from spam bots, you need JavaScript enabled to view it

Consult marketing authorization holder, if you want more information about the medicine.

The latest date of approval of this package information leaflet was 22.12.2009

The latest review of the package information leaflet is available online at the website of State Medicines Control Agency (SMCA) under the Ministry of Health of the Republic of Lithuania http://www.vvkt.lt/